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1

MR Imaging of Compressive Myelomalacia

Ramanauskas, William L., Wilner, Harvey I., Metes, Joseph J., Lazo, Alfredo, Kelly, John K.

Journal:

Journal of Computer Assisted Tomography

Year:

1989

File:

PDF, 462 KB

1989

2

DUAL SPECIFICITY PROTEIN PHOSPHATASES: Therapeutic Targets for Cancer and Alzheimer's Disease

Ducruet, Alexander P., Vogt, Andreas, Wipf, Peter, Lazo, John S.

Journal:

Annual Review of Pharmacology

Year:

2005

Language:

english

File:

PDF, 467 KB

english, 2005

3

Chemical complementation: A definitive phenotypic strategy for identifying small molecule inhibitors of elusive cellular targets

Andreas Vogt, John S. Lazo

Journal:

Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 297 KB

english, 2005

4

Development of a 384-Well Colorimetric Assay to Quantify Hydrogen Peroxide Generated by the Redox Cycling of Compounds in the Presence of Reducing Agents

Johnston, Paul A., Soares, Karina M., Shinde, Sunita N., Foster, Caleb A., Shun, Tong Ying, Takyi, Harold K., Wipf, Peter, Lazo, John S.

Journal:

Assay and Drug Development Technologies

Year:

2008

Language:

english

File:

PDF, 414 KB

english, 2008

5

Drugging Undruggable Molecular Cancer Targets

Lazo, John S., Sharlow, Elizabeth R.

Journal:

Annual Review of Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

6

Assessing potential limitations when characterising the epibiota of marine megafauna: Effect of gender, sampling location, and inter-annual variation on the epibiont communities of olive ridley sea turtles

Robinson, Nathan J., Figgener, Christine, Gatto, Christopher, Lazo-Wasem, Eric A., Paladino, Frank V., Tomillo, Pilar Santidrián, Zardus, John D., Pinou, Theodora

Journal:

Journal of Experimental Marine Biology and Ecology

Year:

2017

Language:

english

File:

PDF, 469 KB

english, 2017

7

Neurite Extension and Malignancy of Neuroblastoma Cells After Treatment With Prostaglandin E 1 and Papaverine 2

Lazo, John S., Ruddon, Raymond W.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1977

Language:

english

File:

PDF, 692 KB

english, 1977

8

A three-dimensional dementia model reveals spontaneous cell cycle reentry and a senescence-associated secretory phenotype

Porterfield, Veronica, Khan, Shahzad S., Foff, Erin P., Koseoglu, Mehmet Murat, Blanco, Isabella K., Jayaraman, Sruthi, Lien, Eric, McConnell, Michael J., Bloom, George S., Lazo, John S., Sharlow, Eli

Journal:

Neurobiology of Aging

Year:

2020

Language:

english

File:

PDF, 874 KB

english, 2020

9

Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors

Peter Wipf, Diana C. Aslan, Diane K. Luci, Eileen C. Southwick, John S. Lazo

Journal:

Biotechnology and Bioengineering

Year:

2000

Language:

english

File:

PDF, 470 KB

english, 2000

10

Energy-dependent nuclear binding dictates metallothionein localization

Elizabeth S. Woo, Dana Dellapiazza, Angela S. Wang, John S. Lazo

Journal:

Journal of Cellular Physiology

Year:

2000

Language:

english

File:

PDF, 294 KB

english, 2000

11

Optimization of ultrasound contrast agents with computational models to improve selection of ligands and binding strength

Timothy M. Maul, Drew D. Dudgeon, Michael T. Beste, Daniel A. Hammer, John S. Lazo, Flordeliza S. Villanueva, William R. Wagner

Journal:

Biotechnology and Bioengineering

Year:

2010

Language:

english

File:

PDF, 2.32 MB

english, 2010

12

ChemInform Abstract: Combinatorial Chemistry and Contemporary Pharmacology

John S. Lazo, Peter Wipf

Journal:

Year:

2000

File:

PDF, 24 KB

2000

13

ChemInform Abstract: Sulfonylated Aminothiazoles as New Small Molecule Inhibitors of Protein Phosphatases.

Peter Wipf, Diana C. Aslan, Eileen C. Southwick, John S. Lazo

Journal:

Year:

2001

File:

PDF, 28 KB

2001

14

ChemInform Abstract: Synthesis and Biological Evaluation of Deoxypreussomerin A and Palmarumycin CP1 and Related Naphthoquinone Spiroketals.

Peter Wipf, Jae-Kyu Jung, Sonia Rodriguez, John S. Lazo

Journal:

Year:

2001

File:

PDF, 32 KB

2001

15

ChemInform Abstract: New Inhibitors of the Thioredoxin—Thioredoxin Reductase System Based on a Naphthoquinone Spiroketal Natural Product Lead.

Peter Wipf, Tamara D. Hopkins, Jae-Kyu Jung, Sonia Rodriguez, Anne Birmingham, Eileen C. Southwick, John S. Lazo, Garth Powis

Journal:

Year:

2002

File:

PDF, 30 KB

2002

16

Synthesis and Biological Evaluation of Caulibugulones A—E.

Peter Wipf, Beomjun Joo, Theresa Nguyen, John S. Lazo

Journal:

Year:

2004

File:

PDF, 12 KB

2004

17

Halenaquinone and Xestoquinone Derivatives, Inhibitors of Cdc25B Phosphatase from a Xestospongia sp.

Shugeng Cao, Caleb Foster, Marni Brisson, John S. Lazo, David G. I. Kingston

Journal:

Year:

2005

File:

PDF, 13 KB

2005

18

Sesterterpenoids and an Alkaloid from a Thorectandra sp. as Inhibitors of the Phosphatase Cdc25B.

Shugeng Cao, Caleb Foster, John S. Lazo, David G. I. Kingston

Journal:

Year:

2005

File:

PDF, 13 KB

2005

19

Four Diterpenoid Inhibitors of Cdc25B Phosphatase from a Marine Anemone.

Shugeng Cao, Caleb Foster, John S. Lazo, David G. I. Kingston

Journal:

Year:

2006

File:

PDF, 13 KB

2006

20

Automated image-based phenotypic analysis in zebrafish embryos

Andreas Vogt, Andrzej Cholewinski, Xiaoqiang Shen, Scott G. Nelson, John S. Lazo, Michael Tsang, Neil A. Hukriede

Journal:

Developmental Dynamics

Year:

2009

Language:

english

File:

PDF, 1.89 MB

english, 2009

21

Protein phosphorylation in cultured endothelial cells

Ken Mackie, Yvonne Lai, Angus C. Nairn, Paul Greengard, Bruce R. Pitt, John S. Lazo

Journal:

Journal of Cellular Physiology

Year:

1986

Language:

english

File:

PDF, 1.27 MB

english, 1986

22

Solubility, ionization, and partitioning behavior of unsymmetrical disulfide compounds: Alkyl 2-imidazolyl disulfides

Ahmad Hashash, D. Lynn Kirkpatrick, John S. Lazo, Lawrence H. Block

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

23

Solubilization of pulmonary angiotensin-converting enzyme with 1-O-n-octyl-β-d-glucopyranoside

John Stephen Lazo, Dana E. Quinn

Journal:

Analytical Biochemistry

Year:

1980

Language:

english

File:

PDF, 342 KB

english, 1980

24

Chemical modulation of bleomycin induced toxicity

Katherine A. Kennedy, William N. Hait, John S. Lazo

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1986

Language:

english

File:

PDF, 424 KB

english, 1986

25

Halenaquinone and xestoquinone derivatives, inhibitors of Cdc25B phosphatase from a Xestospongia sp.

Shugeng Cao, Caleb Foster, Marni Brisson, John S. Lazo, David G.I. Kingston

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 144 KB

english, 2005

26

Sesterterpenoids and an alkaloid from a Thorectandra sp. as inhibitors of the phosphatase Cdc25B

Shugeng Cao, Caleb Foster, John S. Lazo, David G.I. Kingston

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

27

Four diterpenoid inhibitors of Cdc25B phosphatase from a marine anemone

Shugeng Cao, Caleb Foster, John S. Lazo, David G.I. Kingston

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 169 KB

english, 2005

28

Synthesis of chemoreversible prodrugs of ara-C with variable time-release profiles. Biological evaluation of their apoptotic activity

Peter Wipf, Wenjie Li, Christianah M. Adeyeye, James M. Rusnak, John S. Lazo

Journal:

Bioorganic & Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 1.02 MB

english, 1996

29

Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1

John S. Lazo, Ruth Nunes, John J. Skoko, Pierre E. Queiroz de Oliveira, Andreas Vogt, Peter Wipf

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 415 KB

english, 2006

30

Biological evaluation of newly synthesized quinoline-5,8-quinones as Cdc25B inhibitors

Janine Cossy, Damien Belotti, Marni Brisson, John J. Skoko, Peter Wipf, John S. Lazo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 139 KB

english, 2006

31

Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases

Shugeng Cao, Brian T. Murphy, Caleb Foster, John S. Lazo, David G.I. Kingston

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

32

Chemical Genetic Screening Identifies Critical Pathways in Anthrax Lethal Toxin-Induced Pathogenesis

Rekha G. Panchal, Gordon Ruthel, Katherine C. Brittingham, Douglas Lane, Tara A. Kenny, Rick Gussio, John S. Lazo, Sina Bavari

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 1.04 MB

english, 2007

33

Designing, optimizing, and implementing high-throughput siRNA genomic screening with glioma cells for the discovery of survival genes and novel drug targets

Nikhil G. Thaker, Peter R. McDonald, Fang Zhang, Carolyn A. Kitchens, Tong Ying Shun, Ian F. Pollack, John S. Lazo

Journal:

Journal of Neuroscience Methods

Year:

2010

Language:

english

File:

PDF, 1.49 MB

english, 2010

34

Lead detection in environmental water sample using an organoclay film-based attenuated total reflectance sensor

John Richardson, Amanda Drake, Claire Lazo-Miller, Jennifer Hand, Thomas Morgan, Isabelle Lagadic

Journal:

Sensors and Actuators B: Chemical

Year:

2011

Language:

english

File:

PDF, 823 KB

english, 2011

35

New glycolipid inhibitors of Myt1 kinase

Bing-Nan Zhou, Shoubin Tang, Randall K. Johnson, Michael P. Mattern, John S. Lazo, Elizabeth R. Sharlow, Kim Harich, David G.I. Kingston

Journal:

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

36

The synthesis and cytotoxic activity of some haloacetamidoalkyl β-D-xylopyranosides

Anthony F. Hadfield, John S. Lazo, Alan C. Sartorelli

Journal:

Carbohydrate Research

Year:

1979

Language:

english

File:

PDF, 713 KB

english, 1979

37

Separation of bleomycins and their deamido metabolites by high-performance cation-exchange chromatography

Jehangir S. Mistry, Said M. Sebti, John S. Lazo

Journal:

Journal of Chromatography A

Year:

1990

Language:

english

File:

PDF, 350 KB

english, 1990

38

Separation of Cdc25 dual specificity phosphatase inhibition and DNA cleaving activities in a focused library of analogs of the antitumor antibiotic Dnacin

Peter Wipf, Corey R Hopkins, Eleanor O Phillips, John S Lazo

Journal:

Year:

2002

Language:

english

File:

PDF, 593 KB

english, 2002

39

Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases

Peter Wipf, Diana C. Aslan, Eileen C. Southwick, John S. Lazo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 143 KB

english, 2001

40

New inhibitors of the thioredoxin–thioredoxin reductase system based on a naphthoquinone spiroketal natural product lead

Peter Wipf, Tamara D. Hopkins, Jae-Kyu Jung, Sonia Rodriguez, Anne Birmingham, Eileen C. Southwick, John S. Lazo, Garth Powis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 173 KB

english, 2001

41

Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array

Alexander P Ducruet, Robert L Rice, Kenji Tamura, Fumiaki Yokokawa, Shiho Yokokawa, Peter Wipf, John S Lazo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 492 KB

english, 2000

42

Combinatorial synthesis and biological evaluation of Library of small-molecule Ser/Thr-protein phosphatase inhibitors

Peter Wipf, April Cunningham, Robert L. Rice, John S. Lazo

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.10 MB

english, 1997

43

Cell-Active Dual Specificity Phosphatase Inhibitors Identified by High-Content Screening

Andreas Vogt, Kathleen A Cooley, Marni Brisson, Michael G Tarpley, Peter Wipf, John S Lazo

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 316 KB

english, 2003

44

Desperately Seeking Genotype-Selective Anticancer Agents

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 42 KB

english, 2003

45

Normal-phase and stability-indicating reversed-phase high-performance liquid chromatographic methods for the determination of the novel antitumor agent: 1-methylpropyl-2-imidazolyldisulfide

Ahmad Hashash, D Lynn Kirkpatrick, Merrill J Egorin, Lawrence H Block, John S Lazo

Journal:

Journal of Chromatography B

Year:

2002

Language:

english

File:

PDF, 349 KB

english, 2002

46

Process for the preparation of pathogen-inactivated RBC concentrates by using PEN110 chemistry: preclinical studies

Andrei Purmal, C. Robert Valeri, Walter Dzik, Linda Pivacek, Gina Ragno, Aris Lazo, John Chapman

Journal:

Transfusion (Wiley)

Year:

2002

Language:

english

File:

PDF, 297 KB

english, 2002

47

West Nile virus in blood: stability, distribution, and susceptibility to PEN110 inactivation

Thomas Mather, Tsutomu Takeda, Jodie Tassello, Asa Ohagen, Diana Serebryanik, Ed Kramer, Fred Brown, Robert Tesh, Bernadette Alford, John Chapman, Aris Lazo

Journal:

Transfusion (Wiley)

Year:

2003

Language:

english

File:

PDF, 153 KB

english, 2003

48

Mitotic slippage in non-cancer cells induced by a microtubule disruptor, disorazole C1

Fengfeng L Xu, Youssef Rbaibi, Kirill Kiselyov, John S Lazo, Peter Wipf, William S Saunders

Journal:

BMC Chemical Biology

Year:

2010

Language:

english

File:

PDF, 2.35 MB

english, 2010

49

Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility

Courtney R LaValle, Karla Bravo-Altamirano, Karthik V Giridhar, Jun Chen, Elizabeth Sharlow, John S Lazo, Peter Wipf, Q Jane Wang

Journal:

BMC Chemical Biology

Year:

2010

Language:

english

File:

PDF, 1.95 MB

english, 2010

50

Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells

Kaoru Nemoto, Andreas Vogt, Tetsuya Oguri, John S. Lazo

Journal:

Year:

2004

Language:

english

File:

PDF, 255 KB

english, 2004